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Aurora B is also known as
2024-10-09

Aurora-B is also known as chromosomal passenger protein and localizes at the chromosome arms and at centromeres during prophase. As cell cycle continues, Aurora-B moves towards the inner centromere region followed by the central spindle and cortex during 64c and finally accumulates in the midbody in
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To maintain ATP levels postmortem muscle
2024-10-09

To maintain ATP levels, postmortem muscle mobilizes its glycogen reserves to yield papain inhibitor 6-phsphate that proceeds through glycolysis. Glycogen degradation was affected by the interaction between treatment and time (Pinitiation of the experiment. We expected that if myosin ATPase is limi
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CK is considered a central controller of cellular energy
2024-10-09

CK is considered a central controller of cellular energy homeostasis that catalyzes the reversible transfer of a phosphoryl group from ATP to adenosine diphosphate (ADP) and creatine to produce PCr [5]. This enzyme builds up a large pool of rapidly diffusing PCr for temporal and spatial buffering of
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Comparison of the GLUT positive plus ACLY
2024-10-09

Comparison of the GLUT1-positive plus ACLY negative group with the GLUT1-negative plus ACLY positive group indicated no significant difference with respect to disease-free survival and overall survival. However, some obvious differences in histological types were found in their formation. A previous
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It was reported that overexpression of the
2024-10-09

It was reported that overexpression of the rat ACL gene in tobacco increased the total ACL activity by 4 fold, which increased the production of fatty acids by 16% [8]. Recently, a 1.7-fold increase of fatty acids and 1.9-fold increase of triacylglycerol (TAG) was observed in Aspergillus oryzae with
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br Results br Discussion br Conclusion The
2024-10-09

Results Discussion Conclusion The flux of glucose into cytosolic short chain acyl-CoAs was maintained in pure beta epz in the presence of inhibition of ATP citrate lyase with hydroxycitrate and also in a cell line with >90% ATP citrate lyase knockdown suggesting that a pathway other than t
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The therapeutic potential of ML induced
2024-10-09

The therapeutic potential of ML327-induced MET against cycloheximide solubility of mesenchymal origin has not been explored. In the present study, we hypothesized that induction of MET using ML327 would block the growth of ES cells and sensitize to TRAIL-mediated apoptosis. Herein, we report that M
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Previous research showed that combination of chitosan and
2024-10-09

Previous research showed that combination of chitosan and Palbociclib nanocrystals (CNCs) can produce coating films with superior properties (Naseri, Mathew, Girandon, Fröhlich, & Oksman, 2015). CNCs are crystalline nanometer sized rod-like particles. It has been demonstrated that antimicrobial act
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It has been well established that shortly after
2024-10-09

It has been well established that shortly after systemic inflammation, NADPH oxidase and iNOS activity were increased in the click-it-edu and lead to overproduction of reactive oxygen species (ROS) and NO [66]. Moreover, previous studies indicated that Ang II induced an increased level of NADPH oxi
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Consistent with the in vitro results memantine ameliorated A
2024-10-09

Consistent with the in vitro results, memantine ameliorated Aβ-induced cytotoxicity in rat primary cortical cultures. Studies reported that memantine protected neurons against the damage caused by aggregated Aβ40 or Aβ42 oligomers in vivo[26], [27]. These results suggest that, in addition to its neu
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Second the phosphorylation events e g Thr
2024-10-09

Second, the phosphorylation events (e.g., α-Thr172 and β-Ser108) needed for AMPK activation by small molecules binding at the ADaM or other sites remains unclear. Within the β-GBD, phosphorylation of β1-Ser108 was shown to be required for the activation by small molecules binding in the ADaM site, s
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Additionally we were prompted to validate the protective eff
2024-10-08

Additionally, we were prompted to validate the protective effect of ALDH3A1 by utilizing a human corneal model. Cornea is located in the anterior segment of the eye and thus, is constantly exposed to various environmental stressors that affect the cellular oxidative balance and consequently lead to
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In this article we have outlined the increasing
2024-10-08

In this article, we have outlined the increasing, as yet still circumstantial evidence that the 6TM domains of bacterial ACs might operate as receptors for as yet unknown ligands. Intriguingly, several architectural arguments are also applicable to the 6TM domains of mammalian membrane-bound ACs (mA
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Fmoc-Val-OH B lymphocytes are found in blood lymph nodes
2024-10-08

B lymphocytes are found in blood, lymph nodes, spleen and tonsil and other mucosal tissues [110]. These cells originate in the bone marrow from a common progenitor shared with T, NK, and some DC subsets [111]. Progenitor Fmoc-Val-OH progress through the early stages of maturation, rearranging heavy
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Firms are subject to corporate taxation and
2024-10-08

Firms are subject to corporate taxation, and face either an ACE or a CBIT tax scheme. The two tax regimes achieve financing neutrality by treating debt and equity equally, but differ according to whether deduction of capital costs from the corporate tax everolimus is allowed or not. While ACE allow
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