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Further important evidence for G protein signaling on early
2024-07-02

Further important evidence for G protein signaling on early endosomes has been subsequently obtained for the β2-adrenegic receptor using fluorescently-tagged conformation-sensitive nanobodies selectively recognizing the active receptor and Gs protein [43]. More recently, our group used a combinatio
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Cy5.5 carboxylic acid (non-sulfonated) Molecular simulation
2024-07-02

Molecular simulation has proven useful in describing the dynamics and energetics of NMDA receptor LBD cleft closure and the potentiating role of glycans (Yao et al., 2013, Dai and Zhou, 2013, Dai and Zhou, 2015, Dai and Zhou, 2016, Dutta et al., 2015, Omotuyi and Ueda, 2015, Sinitskiy and Pande, 201
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Using this cheese mimicking matrix we screened the antifunga
2024-07-02

Using this cheese-mimicking matrix, we screened the antifungal activity of 44 LAB fermented milk-based products and 23 LAB isolates used as protective cultures against 4 fungal targets. The LAB were obtained from the culture collections of CIRM-BIA (Centre International de Ressources Microbienne-Bac
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Fish aminopeptidases from Alaska Pollack roe and tuna
2024-07-01

Fish aminopeptidases from Alaska Pollack roe and tuna pyloric caeca have been reported on [12,13]. More recently, we described the purification of a leucine aminopeptidase from the skeletal muscle of the common carp [14], red sea bream [15] and a lysine aminopeptidases from Japanese flounder [16]. T
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thapsigargin OCT also is known as POU F plays
2024-07-01

OCT4 (also is known as POU5F1) plays an important role in embryonic stem cell self-renewal, development and reprogram somatic cell into pluripotent stem cell [[5], [6], [7]]. Recently, many studies also find OCT4 promotes the progression of many tumors. For example, Wnt/β-catenin promotes the expans
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The disease stimulatory effects of hyperadiponectinemia in p
2024-07-01

The disease-stimulatory effects of hyperadiponectinemia in patients contradict a previous view based on studies of preclinical models showing that APN might be beneficial for AD [8]. Indeed, despite the action of APN as a risk factor in patients with AD, APN is protective against oxidative stress-in
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Mitochondria from frozen thawed bull sperm are
2024-07-01

Mitochondria from frozen-thawed bull sperm are capable of producing energy using pyruvate and lactate as substrates through oxidative pathways (Beorlegui et al., 1997). Based on the present study, heparin capacitated sperm had a lesser lactate concentration in the incubation medium, supporting the h
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The AR signalling pathways play important roles
2024-07-01

The AR signalling pathways play important roles in several physiopathological processes associated with ischaemia, inflammation, and tumourigenesis [35]. Moreover, A3AR is overexpressed in different tumour AS-703026 synthesis and seems implicated in pro- or anti-apoptotic effects [36]. In particular
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br Introduction Cell motility is fundamentally
2024-07-01

Introduction Cell motility is fundamentally important in morphogenesis, wound healing, and the immune response. One of the best-studied basic types of cell movement is lamellipodial motility [1, 2], characterized by a thin (∼0.1–0.2 μm), broad (∼10–40 μm) motile appendage containing a dynamic fla
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In the previous study we demonstrated the importance of
2024-07-01

In the previous study, we demonstrated the importance of the mPFC postsynaptic 5-HT1A receptor in the sustained antidepressant effects, because a sustained antidepressant effect was obtained with intra-mPFC injection, but not systemic injection of 8-OH-DPAT, a 5-HT1A receptor agonist (Fukumoto et al
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On the contrary evidence also suggests that
2024-07-01

On the contrary, evidence also suggests that autophagy plays a striking protective role in cancer cells. Highly burgeoning cancer Solithromycin require cellular building blocks for their metabolism and energy production. At this stage of cancer development, autophagy acts as a friend providing all t
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br Viral manipulation of host factors to oppose anti
2024-07-01

Viral manipulation of host factors to oppose anti-viral autophagy To escape or manipulate autophagy, some viruses developed strategies that are based on the recruitment of host-cell endogenous factors. The non-enveloped double-stranded DNA virus adenovirus is rapidly endocytosed after attachment.
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Protein protein interaction networks are an important ingred
2024-07-01

Protein–protein interaction networks are an important ingredient for the system-level understanding of cellular processes. Such networks can be used for filtering and assessing functional genomics data and for providing an instinctive platform for annotating structural, functional and evolutionary p
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In our previous report salivary arginase
2024-07-01

In our previous report, salivary arginase levels were found to be higher in periodontitis patients compared to healthy controls (Ozmeriç, Elgün, & Uraz, 2000). However, only one study has investigated arginase ezyme in saliva in patients with dental implants in which smokers were also included. An i
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br Application of bamboo in the food and
2024-07-01

Application of bamboo in the food and pharmaceutical industry For decades, the application of antioxidants in the food and pharmaceutical industry has been widespread. In the past, antioxidants were previously used to control oxidation and retard spoilage but today, many are used because of putat
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